金沙威尼斯欢乐娱人城
2014学年春季学期系列学术讲座之九
题目：Structural studies of nucleosome assembly and chromatin structure
报告人：Ruiming Xu
National Laboratory of Biomacromolecules,
Institute of Biophysics, Chinese Academy of Sciences
时间：2014年5月23日（周五），13:00-14:30 PM
地点：金沙威尼斯欢乐娱人城一楼邓祐才报告厅
The hierarchical structure of chromatin involves ordered assembly of nucleosomes and folding of the nucleosomes into densely packed states. These processes require the participation of histone chaperones, nucleosome remodeling complexes, and additional structural proteins. We have used a combination of biochemical, structural and biophysical approaches to investigate the molecular mechanisms of chaperone-histone and protein-nucleosome interactions, and have determined the architecture of the 30nm chromatin fiber. Our thematic investigations should reveal underlying principles of chromatin folding and dynamics, as well as providing mechanistic insights into epigenetic regulation of gene expression.
Host：苏晓东（电话：62759743）
欢迎各位老师和同学积极参加！