金沙威尼斯欢乐娱人城2015年度秋季学期学术系列讲座之十

题目：Taste processing in Drosophila

讲座人：Kristin Scott, Ph.D.

Professor

University of California, Berkeley

时间：2015年12月11日，13:00-14:30

地点：金沙威尼斯欢乐娱人城邓祐才报告厅

联系人：董一言（医学部基础医学） 陈金琳（金沙威尼斯欢乐娱人城）

dongyiyan@pku.edu.cn

摘要：The ability to identify food that is nutrient-rich and avoid toxic substances is essential for an animal`s survival.  Although olfaction and vision contribute to food detection, the gustatory system acts as a final checkpoint control for food acceptance or rejection.  The fruit fly Drosophila melanogaster tastes many of the same stimuli as mammals and provides an excellent model system for comparative studies of taste detection.  The relative simplicity of the fly brain and behaviors, along with the molecular genetic and functional approaches available in Drosophila, allow the examination of gustatory neural circuits from sensory input to motor output.  We have utilized a combination of molecular, behavioral, and calcium imaging studies to determine the taste ligands that different gustatory neurons detect and how taste information is processed in the higher brain.  More recently, we have begun to examine how hunger, satiety and learning influence activity in taste circuits and regulate feeding decisions. These studies provide insight into how taste compounds are detected and processed by the brain.

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